Clindamycin is an antibiotic drug categorized as a lincosamide which works by inhibiting bacterial protein synthesis. The drug is given to prevent or treat bacterial infections.
It is also applied topically on the skin as an ointment for prevention or treatment of acne. Similar with any medication, it has its share of side effects and some can be severe. Most individuals do not end up with all the possible side effects though.
Digestive side effects of clindamycin
As an antibiotic, clindamycin can trigger digestive issues. The usual side effects include:
- Nausea
- Diarrhea
- Vomiting
- Constipation
- Abdominal pain
Some might complain of a metallic taste in the mouth while under treatment. In some cases, inflammation of the colon or colitis can also occur. Around 10% of cases might end up with Clostridium difficile-associated diarrhea up to several months after using the drug.
If the individual has severe or blood-streaked diarrhea, a doctor should be seen as soon as possible.
Topical effects
If clindamycin is applied on the skin for prevention or treatment of acne, it can cause dryness and redness. Burning, itchiness and peeling can also occur. In case it is used vaginally, fungal infections can develop.
Other side effects
The drug can also cause headache, fever, sore throat or back pain. Urinary tract issues such as diminished urine production, protein in the urine or urinary tract infection can also develop.
In rare instances, the drug can cause blood abnormalities such as reduced white blood cells or platelets. If the platelet count is low, it manifests as bleeding or bruising. In addition, the skin turns yellowish which is called jaundice if the liver is impaired by the drug.
Potential for allergic reactions
The indications of an allergic reaction to clindamycin include:
- Hives
- Rashes
- Difficulty breathing
- Facial swelling
- Itchiness
- Wheezing
If anaphylaxis occurs, it can lead to low blood pressure and collapse. For mild symptoms, antihistamines are generally given while severe reactions require corticosteroids to lessen the swelling.